PAK6 Polyclonal Antibody Store at -20°C
SKU: E-AB-14280-200
PAK6 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14280 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PAK6 |
| Abbre | PAK6 |
| Synonyms | CDKN1A activated kinase 6, EC 2.7.1.37, PAK 5, PAK 6, PAK-5, PAK-6, PAK5, PAK6, Pak6, Serine threonine protein kin, p21 activated protein kinase 6, p21 protein (Cdc42/Rac)-activated kinase 6, p21(CDKN1A) activated kinase 6, p21-activated kinase 6, p21activated kinase 6 |
| Swissprot | |
| Cellular Localization | Nucleus, fibrillar center, nucleus, Other locations: cell junction, cytoplasm. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:100 |
Background
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.