P2RX3 Polyclonal Antibody Store at -20°C
SKU: E-AB-13478-200
P2RX3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13478 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human P2RX3 |
| Abbre | P2RX3 |
| Synonyms | ATP receptor, MGC129956, P2RX3, P2X purinoceptor 3, P2X receptor subunit 3, P2X3, P2rx3, Purinergic receptor, Purinergic receptor P2X ligand gated ion channel 3, Purinergic receptor P2X3, Purinoceptor P2X3 |
| Swissprot | |
| Calculated MW | 44 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
| IHC | 1:25-1:100 |
Background
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.