NEK11 Polyclonal Antibody
SKU: E-AB-10921-200
NEK11 Polyclonal Antibody
| SKU # | E-AB-10921 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human NEK11 |
| Abbre | NEK11 |
| Synonyms | 4932416N14Rik, FLJ23495, NEK11, NEK11S/L, NIMA (never in mitosis gene a) related kinase 11, NIMA (never in mitosis gene a)- related kinase 11, NIMA related kinase 11L, NIMA related kinase 11S, NIMA-related kinase 11, Never in mitosis A-related kinase 11, NimA |
| Swissprot | |
| Calculated MW | 74 kDa |
| Cellular Localization | Nucleus. Nucleus>nucleolus. Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S-arrested cells. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.