KCTD16 Polyclonal Antibody Reactivity Mouse
SKU: E-AB-52282-200
KCTD16 Polyclonal Antibody Reactivity Mouse
| SKU # | E-AB-52282 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human KCTD16 |
| Abbre | KCTD16 |
| Synonyms | BTB/POZ domain containing protein KCTD16, BTB/POZ domain-containing protein KCTD16, DKFZp781A1155, KCD16, KCTD16, KIAA1317, MGC138167, Potassium, Potassium channel tetramerisation domain containing 16, Potassium channel tetramerization domain containing protein 16 |
| Swissprot | |
| Calculated MW | 49 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cell junction>synapse>presynaptic cell membrane. Cell junction>synapse>postsynaptic cell membrane. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD16 (potassium channel tetramerisation domain containing 16), also known as BTB/POZ domain-containing protein KCTD16, is a 428 amino acid protein that contains one BTB (POZ) domain. An auxiliary subunit of GABAB R1 and GABAB R2, KCTD16 increases agonist potency and alters the G-protein signaling of the receptors by accelerating onset and promoting desensitization.