KCNA5 Polyclonal Antibody Store at -20°C
SKU: E-AB-14174-200
KCNA5 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14174 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human KCNA5 |
| Abbre | KCNA5 |
| Synonyms | ATFB7, HCK1, HK2, HPCN1, KCNA5, KV1.5, PCN1, Potassium channel, Potassium voltag, cardiac potassium channel, insulinoma and islet cell, insulinoma and islet potassium channel, member 5, potassium channel 1, shaker-related subfamily, voltage-gated |
| Swissprot | |
| Calculated MW | 67 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints.Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily.This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment.It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion.This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12.Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7).