ILKAP Polyclonal Antibody Reactivity Human
SKU: E-AB-52624-200
ILKAP Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52624 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ILKAP |
| Abbre | ILKAP |
| Synonyms | ILKAP, ILKAP2, ILKAP3, PP2C-DELTA, PPM1O, DKFZp434J2031, FLJ10181, Integrin linked kinase associated phosphatase, Integrin linked kinase associated serine/threonine phosphatase, Integrin linked kinase associated serine/threonine phosphatase 2C, Integrin-linked kinase-associated serine/threonine phosphatase 2C, MGC4846, PP2C DELTA, Protein phosphatase 2c delta isozyme |
| Swissprot | |
| Calculated MW | 43 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:300 |
Background
The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.ILKAP (ILK Associated Serine/Threonine Phosphatase) is a Protein Coding gene. Among its related pathways are AKT Signaling Pathway. GO annotations related to this gene include protein serine/threonine phosphatase activity. An important paralog of this gene is PPM1F.