HSD3B2 Polyclonal Antibody Store at -20°C
SKU: E-AB-15114-200
HSD3B2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15114 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HSD3B2 |
| Abbre | HSD3B2 |
| Synonyms | HSD3B, HSDB, SDR11E2 |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum, endoplasmic reticulum, endoplasmic reticulum membrane, smooth endoplasmic reticulum membrane, Mitochondrion, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial membrane, Other locations: integral component of membrane. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:25-1:100 |
Background
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.