GUCA1A Polyclonal Antibody Reactivity Human
SKU: E-AB-53078-200
GUCA1A Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53078 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human GUCA1A |
| Abbre | GUCA1A |
| Synonyms | COD3, GCAP, GCAP 1, GUC1A, GUCA, GUCA1, GUCA1A, Guanylate Cyclase Activating Protein Photoreceptor 1, Guanylate cyclase activator 1A, Guanylin 1, Guanylyl cyclase-activating protein 1, guanylyl cyclase activating protein 1 |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 0.72 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:100 |
Background
This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants.