GCSAM Polyclonal Antibody
SKU: E-AB-13261-200
GCSAM Polyclonal Antibody
| SKU # | E-AB-13261 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GCSAM |
| Abbre | GCSAM |
| Synonyms | GCAT2, GCET2 germinal center expressed transcript 2, GCET2 germinal centre expressed transcript 2, GCSAM, Gcet, Gcsam, Germinal center B cell associated protein 2, Germinal center B-, Germinal center associated lymphoma, Germinal center associated lymphoma protein |
| Swissprot | |
| Cellular Localization | Cytoplasm. Cell membrane. It relocalizes from the cytoplasm to podosome-like structures upon cell treatment with IL6. |
| Concentration | 1.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas.It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites.In B cells, its expression is specifically induced by interleukin-4.Alternative splicing results in multiple transcript variants encoding different isoforms.