ELMO1 Polyclonal Antibody
SKU: E-AB-52186-200
ELMO1 Polyclonal Antibody
| SKU # | E-AB-52186 |
| Reactivity |
Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Abbre | ELMO1 |
| Synonyms | CED 12, CED-12, CED12, Ced 12 homolog, Ced 12 homolog 1, Ced12 homolog, Ced12 homolog 1, ELMO 1, ELMO-1, ELMO1, Elmo1, Engulfment and cell motility 1, Engulfment and cell motility protein 1, KIAA0281, MGC126406, Protein ced-12 homolog |
| Swissprot | |
| Cellular Localization | Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants.