DPYSL3 Polyclonal Antibody Store at -20°C
SKU: E-AB-11167-200
DPYSL3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11167 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human DPYSL3 |
| Abbre | DPYSL3 |
| Synonyms | CRMP 4, CRMP-4, CRMP4, Collapsin response mediator protein 4, Collapsin response mediator protein 4 long, DPYL3, DPYSL3, DRP 3, DRP-3, DRP3, Dihydropyrimidinase like 3, Dihydropyrimidinase related protein 3, Dihydropyrimidinase-related protein 3, LCRMP, TUC4, ULI, ULIP 1 |
| Swissprot | |
| Calculated MW | 62 kDa |
| Cellular Localization | Cytoplasm. Cell projection>growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. Developing neurons in the adult hippocampus of mammals, known as the dentate gyrus, express CRMP-4. Rodent neocortical neurons express CRMP-4 in the perikaryon, in neurites and at growth cones.