DIABLO Polyclonal Antibody Store at -20°C
SKU: E-AB-14352-200
DIABLO Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14352 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human DIABLO |
| Abbre | DIABLO |
| Synonyms | 0610041G12Rik, DBLOH, DBOH, DFNA64, DIABLO S, Diablo IAP binding mitochondrial protein, Diablo homolog, Diablo homolog (Drosophila), Diablo homolog mitochondrial, Diablo like protein, Direct IAP binding protein with low pI, Direct IAP-binding protein with low, diablo |
| Swissprot | |
| Calculated MW | 27 kDa |
| Cellular Localization | Mitochondrion. Released into the cytosol when cells undergo apoptosis. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:50-1:200 |
Background
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes. Isoform 3 is ubiquitously expressed.