CK14 Polyclonal Antibody
SKU: E-AB-40480-200
CK14 Polyclonal Antibody
| SKU # | E-AB-40480 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human Keratin, type I cytoskeletal 14 protein |
| Abbre | CK14 |
| Synonyms | CK-14, Cytokeratin 14, Cytokeratin-14, Cytokeratin14, Dowling Meara, Dowling-Meara, EBS3, EBS4, Epidermolysis bullosa simplex, K14, K1C14, Keratin, Keratin 14, Keratin 14 (epidermolysis bullosa simplex, Keratin type I cytoskeletal 14, Koebner, ck14, CK 14 |
| Swissprot | |
| Calculated MW | 51 kDa |
| Observed MW | 51 kDa
|
| Cellular Localization | Cytoplasm, Intermediate filament, Keratin, Nucleus. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:30000-1:100000 |
Background
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.