BHMT2 Polyclonal Antibody Reactivity Human
SKU: E-AB-52473-200
BHMT2 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52473 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human BHMT2 |
| Abbre | BHMT2 |
| Synonyms | Betaine homocysteine S methyltransferase 2, Betaine homocysteine methyltransferase 2, EC 2.1.1.5, FLJ20001 , S methylmethionine homocysteine S methyltransferase BHMT2, SMM hcy methyltransferase |
| Swissprot | |
| Calculated MW | 40 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasmic |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:30-1:150 |
Background
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.