ASS1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52452-200
ASS1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52452 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ASS1 |
| Abbre | ASS1 |
| Synonyms | ASS, ASSA, ASSY, Argininosuccinate synthase, Argininosuccinate synthase 1, Argininosuccinate synthetase 1, Ass-1, CTLN1, Citrulline aspartate ligase, Citrulline--aspartate ligase, ass1 |
| Swissprot | |
| Calculated MW | 47 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome, Mitochondrion, Other locations: cytoplasm, myelin sheath. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
ASS1 is a rate-limiting enzyme in the urea cycle. Citrullinemia type I is an autosomal recessive disorder that is caused by a deficiency of the urea cycle enzyme argininosuccinate synthetase (ASS1). Deficiency of ASS1 shows various clinical manifestations encompassing severely affected patients with fatal neonatal hyperammonemia as well as asymptomatic individuals with only a biochemical phenotype.