AP1S3 Polyclonal Antibody Reactivity Human
SKU: E-AB-53014-200
AP1S3 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53014 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human AP1S3 |
| Abbre | AP1S3 |
| Synonyms | AP-1 complex subunit sigma-3, AP1S3, Adapter-related protein complex 1 subunit sigma-1C, Adaptor protein complex AP 1 sigma 1C subunit, Adaptor protein complex AP-1 subunit sigma-1C, Adaptor related protein complex 1 sigma 3 subunit, Ap1s3, Clathrin assembly pro |
| Swissprot | |
| Cellular Localization | Golgi apparatus. Cytoplasmic vesicle membrane. Membrane>clathrin-coated pit. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants.