ALDH6A1 Polyclonal Antibody Store at -20°C
SKU: E-AB-10769-200
ALDH6A1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10769 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ALDH6A1 |
| Abbre | ALDH6A1 |
| Synonyms | 1110038I05Rik, AI314632, ALDH6A1, Aldehyde dehydrogenase 6 family member A1, Aldehyde dehydrogenase family 6, Aldehyde dehydrogenase family 6 member A1, Malonate semialdehyde dehydrogenase, Malonate-semialdehyde dehydrogenase [acylating], Methylmalon, subfamily A1 |
| Swissprot | |
| Calculated MW | 58 kDa |
| Cellular Localization | Mitochondrion. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.