AATK Polyclonal Antibody Store at -20°C
SKU: E-AB-13451-200
AATK Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13451 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human AATK |
| Abbre | AATK |
| Synonyms | AATK, AATYK, AATYK1, Apoptosis associated tyrosine kinase, Apoptosis-associated tyrosine kinase, Brain apoptosis associated tyrosine kinase, Brain apoptosis-associated tyrosine kinase, CDK5 binding protein, CDK5-binding protein, KIAA0641, LM, Lemur tyrosine kinase 1 |
| Swissprot | |
| Cellular Localization | Membrane. Cytoplasm. Cytoplasm>perinuclear region. Predominantly perinuclear. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene.