ZWINT Polyclonal Antibody Store at -20°C
SKU: E-AB-14670-200
ZWINT Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14670 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ZWINT |
| Abbre | ZWINT |
| Synonyms | HZwint 1, HZwint1, Human ZW10 interacting protein 1, KNTC 2 AP, KNTC2AP, MGC 117174, MGC117174, Z, ZW10 interacting kinetochore protein, ZW10 interacting protein 1, ZW10 interactor, ZW10-interacting protein 1, ZWINT, ZWINT 1, Zwint-1, kinetochore protein |
| Swissprot | |
| Cellular Localization | Nucleus. Chromosome>centromere>kinetochore. Localizes to kinetochores from late prophase to anaphase. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known.It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores.The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase.It has a uniform distribution in the cytoplasm of interphase cells.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.