WWP1 Polyclonal Antibody Reactivity Mouse
SKU: E-AB-52241-200
WWP1 Polyclonal Antibody Reactivity Mouse
| SKU # | E-AB-52241 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human WWP1 |
| Abbre | WWP1 |
| Synonyms | AIP 5, AIP5 , Atropin-1-interacting protein 5, NEDD4-like E3 ubiquitin-protein ligase WWP1, Nedd 4 like ubiquitin protein ligase, TGIF interacting ubiquitin ligase 1, Tiul1, WW domain containing E3 ubiquitin protein ligase 1, WW domain-containin, hSDRP1, nedd4 like |
| Swissprot | |
| Calculated MW | 105 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cell membrane, Cytoplasmic and Nuclear. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes.