Product Details
Formal Name: (3β, 23β)-14,15,16,17-Tetrahydroveratraman-3,23-diol
Alternate Names: NSC 17821; NSC 23880
Molecular Formula: C27H39NO2
Formula Weight: 409.60
CAS Number: 60-70-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 12 mg/ml) or in Ethanol (up to 10 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Cyclopamine analog
Functions
Veratramine is a teratogenic steroidal alkaloid found in the corn lily (Veratrum sp.). It is an analog of cyclopamine which can inhibit the hedgehog signaling pathway-dependent proliferation in NIH/3T3 cells at 8 μM. Cell permeable. SPECIAL HANDLING PRECAUTIONS: This product is teratogenic. Women who are, or may be pregnant should not handle this compound.
Application Procedures
First dissolved in DMSO (up to 12 mg/ml) or in Ethanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.