Tribioscience Troglitazone, PPARg Agonist (TBI1046)
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Tribioscience Troglitazone, PPARg Agonist (TBI1046)
Research Use Only. Not intended for human use.
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Product Details
Formal Name:Â 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride
Molecular Formula:Â C24H27NO5S
Formula Weight:Â 441.55
CAS Number:Â 97322-87-7
Purity:Â >98%
Formulation:Â powder
Solubility:Â Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Storage:Â RT
Stability: ≥ 1 year.
Applications
PPARg agonist
Functions
PPARgamma agonist. Stimulates recruitment of transcriptional coactivators to PPARgamma at 1 µM. Stimulates adipogenesis in human mesenchymal stem cells.  Induces apoptosis in a variety of tumor cells lines. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.