Product Details
Formal Name: (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile, hydrochloride
Alternate Names: BMS-477118
Molecular Formula: C18H25N3O2·HCl
Formula Weight: 416.40
CAS Number: 709031-78-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
DPP-IV inhibitor
Functions
Saxagliptin is a clinically useful DPPIV inhibitor for the treatment of diabetes. Human DPP-IV Ki = 0.6 nM.
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.