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Tribioscience Rimonabant, CB1 Antagonist (TBI1059)

Tribioscience Rimonabant, CB1 Antagonist (TBI1059)

SKU: TBI1059-10MG

  • $ 10795


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Tribioscience Rimonabant, CB1 Antagonist (TBI1059)

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Product Details

Formal Name: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-yl-1H-pyrazole-3-carboxamide

Alternate Names: Acomplia; SR141716

Molecular Formula: C22H21Cl3N4O

Formula Weight: 463.8

CAS Number: 168273-06-1

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).

Storage: Room temperature

Stability: ≥ 1 year.

Applications

CB1 antagonist

Functions

Rimonabant is a selective CB1 receptor inverse agonist (Ki = 1.8 nM). It is an anorectic antiobesity drug originally approved for use in Europe but eventually withdrawn from the market because of potential severe psychiatric side effects.

Application Procedures

First dissolved in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.