Description
Interleukin-10 (IL-10) is an anti-inflammatory cytokine predominantly produced by monocytes and, to a lesser extent, by lymphocytes. It plays a crucial role in inducing regulatory T cells (Tregs) in vitro and is characteristically associated with CD4+ Treg lymphocytes. IL-10 inhibits the proliferation of CD4+ T cells, including Th1 and Th2 subsets, and suppresses the cytotoxic functions of cytotoxic T lymphocytes. Beyond monocytes and lymphocytes, IL-10 is produced by various cell types, such as T-cells, macrophages, and mast cells.
Product Details
Alternative names: cytokine synthesis inhibitory factor; CSIF; GVHDS; IL-10; IL10A; T-cell growth inhibitory factor; TGIF; Interleukin-10
Molecular Weight: 18.78 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4.
Concentration: 0.5mg/mL
Purity: > 95% by SDS-PAGE
Application: SDS-PAGE
Storage Condition: Store at -20°C to -80°C for up to 12 months. Avoid repeated freeze-thaw cycles.