Product Details
Formal Name: From Mycale sp.
Molecular Formula: C52H74N4O17
Formula Weight: 1027.16
CAS Number: 122752-21-0
Purity: >98%
Formulation: Lyophilized
Solubility: Soluble in DMSO (up to 20 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Actin depolymerizing agent
Functions
A novel marine natural product which binds to actin in a 1:1 molar ratio (Kd=13-20 nM).1 It selectively and completely depolymerizes F-actin to G-actin via a novel mechanism different from that of the cytochalasin D.2 It is a novel and specific inhibitor of actomyosin ATPase.3
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.