Product Details
Formal Name: N-[4-(2-{[2-(4-Methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide
Alternate Names: Tikosyn
Molecular Formula: C19H27N3O5S2
Formula Weight: 441.56
CAS Number: 115256-11-6
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: RT
Stability: ≥ 1 year.
Applications
Herg channel blocker
Functions
Dofetilide is a clinically useful class III antiarrhythmic that inhibits the rapid component of the delayed rectifier outward potassium current (IKr) via selective blockage of the Kv11.1 (hERG) channel.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.