Tribioscience CYM5541, Allosteric Sphingosine-1-Phosphate Receptor 3 Agonist (TBI4493)

Tribioscience CYM5541, Allosteric Sphingosine-1-Phosphate Receptor 3 Agonist (TBI4493)

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Product Details

Formal Name: N,N-Dicyclohexyl-5-cyclopropyl-1,2-oxazole-3-carboxamide

Alternate Names: ML249

Molecular Formula: C₁₉H₂₈N₂O₂

Formula Weight: 316.44

CAS Number: 945128-26-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 15 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

Allosteric sphingosine-1-phosphate Receptor 3 agonist

Functions

CYM-5541 is a potent and selective allosteric agonist of the Sphingosine-1-phosphate Receptor 3 (S1P3; EC50’s = 72.3-132 nM).

Application Procedures

First dissolved in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.