Tribioscience CVPA, Aquaporin 1 Blocker (TBI1430)

Tribioscience CVPA, Aquaporin 1 Blocker (TBI1430)

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Product Details

Formal Name: 3-[3-(2-Carboxy-vinyl)-phenyl]-acrylic acid

Alternate Names: 3,3′-(1,3-Phenylene)bis(2-propenoic acid)

Molecular Formula: C₁₂H₁₀O₄

Formula Weight: 218.21

CAS Number: 37710-81-9

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 25 mg/ml).

Storage: Room temperature

Stability: ≥ 2 years.

Applications

Aquaporin 1 blocker

Functions

Aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.