Tribioscience Anti-Mouse PDGFRα Rat Monoclonal Antibody (TBS10195)

Description: Platelet-derived growth factor receptor alpha (PDGFRα) is a receptor located on the surface of a wide range of cell types. This receptor binds to certain isoforms of platelet-derived growth factors (PDGFs) and becomes active in stimulating cell signaling pathways that elicit responses such as cellular growth and differentiation. PDGFRα is involved in various physiological and pathological processes, including wound healing, tissue repair, and the development of mesenchymal cell types. It plays a critical role in the regulation of cell migration, proliferation, and chemotaxis, particularly in fibroblasts and vascular smooth muscle cells.

Alternative name: alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; CD140a; EC 2.7.10; EC 2.7.10.1; MGC74795; PDGF-alpha; PDGF R alpha; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA/BCR fusion; PDGF-R-alpha; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA

Applications:

• In vivo blocking of PDGFRα
• In vitro of PDGFRα
• Immunohistochemistry
• Flow cytometry
• Western blot
• ELISA

Molecular Weight: 150 kDa

Immunogen: Recombinant mouse PDGFRα

Host: Rat

Isotype: Rat IgG2a, kappa

Concentration: 4 mg/ml

Purity: >95%

Formulation: PBS, pH 7.0, No stabilizers or preservatives.

Endotoxin: < 2EU/mg

Clonality: Monoclonal

Sterility: 0.2µm filtered

Storage: 4°C stable for 2years. Store at -20 °C for long-term.