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Description: Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor expressed on the surface of immune cells, including T cells, B cells, and myeloid cells. It plays a crucial role in immune regulation by delivering inhibitory signals upon interaction with its ligands, PD-L1 and PD-L2, to reduce T cell activity and maintain immune homeostasis.
Applications:
- in vivo blocking of PD-1/PD-L signaling
- in vitro PD-1 neutralization
- Immunohistochemistry (frozen)
- Immunofluorescence
- Western blot
- Flow cytometry
Molecular Weight: 150 kDa
Host: Rat
Isotype: Rat IgG2a
Concentration: 4 mg/ml
Purity: >95%
Formulation: PBS, pH 7.0, no stabilizers or preservatives.
Endotoxin: < 2EU/mg
Clonality: Monoclonal
Sterility: 0.2 µm filtered
Storage: Stable at 4°C for three months. Store at -20°C for long-term storage.