Tribioscience Anti-Mouse CD8α Rat Monoclonal Antibody (TBS10199)

Description: CD8A is a gene that encodes the CD8 antigen, a cell surface glycoprotein primarily found on cytotoxic T cells (CD8+ T cells).  The CD8 antigen acts as a coreceptor with the T-cell receptor (TCR) to recognize antigens presented by class I MHC molecules on antigen-presenting cells. CD8A is a significant prognostic marker in various cancers, including bladder cancer (BCa), hepatocellular carcinoma, metastatic melanoma, and head and neck squamous cell carcinoma.

Applications:

• in vivo CD8+ T cel depletion
• Western blot

Molecular Weight: 150 kDa

Immunogen: Mouse CTL clone L3

Host: Rat

Isotype: Rat IgG2b, kappa

Concentration: 4 mg/ml

Purity: >95%

Formulation: PBS, pH 7.0, No stabilizers or preservatives.

Endotoxin: < 2EU/mg

Clonality: Monoclonal

Sterility: 0.2 µm filtered

Storage:  Store at 4°C for one month. Store at -20°C for long-term storage.