Tribioscience Anti-Human CD19 Mouse Monoclonal Antibody (TBS10203)

Description: CD19 is a 95 kDa transmembrane glycoprotein of the immunoglobulin superfamily, specifically expressed on B cells. It serves as a key cell surface antigen for B cell identification and is present throughout B cell development, from early stages in the bone marrow to mature B cells in peripheral blood. CD19 is a critical target in CAR T cell therapies for B cell malignancies, including chronic lymphocytic leukemia (CLL) and B cell non-Hodgkin lymphoma (NHL). CAR T cells designed to target CD19 have demonstrated significant clinical efficacy in treating these conditions.

Applications:

• Flow cytometry
• Functional assays
• Immunofluorescence
• Chimeric antigen receptor construction

Molecular Weight: 150 kDa

Host: Mouse

Isotype: Mouse IgG1

Concentration: 4 mg/ml

Purity: >95%

Formulation: PBS, pH 7.0, no stabilizers or preservatives.

Endotoxin: < 2EU/mg

Clonality: Monoclonal

Sterility: 0.2 µm filtered

Storage: Store at 4°C for one month. Store at -20°C for long-term storage.

otoxin: < 1.0 EU/mg

Clonality: Monoclonal

Sterility: 0.2 µm filtered

Storage: 2-8°C for up to one month. Store at ≤ -70°C for long-term.