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Tribioscience Andrographolide, Induces Mitochondrial-Mediated Apoptosis (TBI1173)

Tribioscience Andrographolide, Induces Mitochondrial-Mediated Apoptosis (TBI1173)

SKU: TBI1173-100MG

  • $ 6095


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Tribioscience Andrographolide, Induces Mitochondrial-Mediated Apoptosis (TBI1173)

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Product Details

Molecular Formula: C20H30O6

Formula Weight: 350.45

CAS Number: 5508-58-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 8 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

Induces mitochondrial-mediated apoptosis

Functions

Major bioactive component of the medicinal plant Andrographis paniculate.   Demonstrates anti-inflammatory anti-apoptotic, anti-viral and anti-proliferative effects in vitro and in vivo.  Prevents hyperglycemia in rat diabetes model.    Irreversible antagonist of NK-κB and AP-1 (IC50 = 15 µM)

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 8 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 3 months.