First dissolved in Water (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in water may be stored at -20°C for up to 2 months.
Tribioscience 5-Thio-D-Glucose, Glucose Transport Inhibitor (TBI1398)
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Tribioscience 5-Thio-D-Glucose, Glucose Transport Inhibitor (TBI1398)
Research Use Only. Not intended for human use.
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Product Details
Formal Name: 5-Thio-5-deoxy-D-glucose
Alternate Names: 5-TG
Molecular Formula: C6H12O5S
Formula Weight: 196.20
CAS Number: 20408-97-3
Purity: >97%
Formulation: powder
Solubility: Soluble in Water (up to 15 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
Glucose transport inhibitor
Functions
A potent competitive inhibitor of the cellular transport of glucose and glucose-mediated insulin release. May be used to induce a state of glucose deprivation in laboratory animals. Stimulates feeding in rat models. Induces Alzheimer-like changes in frontal cortex and hippocampus in rats. Elevates renal TGF-b1 at a dose that does not prevent streptozotocin diabetes in rats.
Application Procedures