TNXB Polyclonal Antibody Store at -20°C
SKU: E-AB-12899-200
TNXB Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12899 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human TNXB |
| Abbre | TNXB |
| Synonyms | EDS3, Ehlers Danlos like syndrome, Growth inhibiting protein 45, HXBL, Hexabrachion like protein, Hexabrachion-like protein, NXB2, TENX, TN X, TN-X, TNX, TNXB, TNXB1, TNXB2, TNXBS, Tenascin X precursor, Tenascin XB, Tenascin XB1, Tenascin XB2, Tenascin-X, VUR8, XB, XBS |
| Swissprot | |
| Cellular Localization | Secreted>extracellular space>extracellular matrix. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.