THOC7 Polyclonal Antibody Store at -20°C
SKU: E-AB-10940-200
THOC7 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10940 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human THOC7 |
| Abbre | THOC7 |
| Synonyms | FLJ23445, Functional spliceosome associated protein 24, Functional spliceosome-associated protein 24, Ngg1 interacting factor 3 like 1 binding protein 1, Ngg1 interacting factor 3 like protein 1 binding protein 1, Ngg1-interacting factor 3-like , fSAP24, hTREX30 |
| Swissprot | |
| Calculated MW | 24 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Interaction with THOC5 is required for nuclear localization. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
NIF3L1 BP1 (Ngg1-interacting factor 3-like 1 binding protein 1), also known as THOC7 (THO complex subunit 7 homolog), fSAP24 or hTREX30, is a 204 amino acid cytoplasmic and nuclear protein that belongs to the THOC7 family and interacts with NIF3L1.NIF3L1 BP1 is a component of the THO/TREX complex that is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling Pol II with RNA splicing and export factors.The THO/TREX complex also plays a role in the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.The gene that encodes NIF3L1 BP1 maps to human chromosome 3p14.1.