SRGN Polyclonal Antibody Store at -20°C
SKU: E-AB-11601-200
SRGN Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11601 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SRGN |
| Abbre | SRGN |
| Synonyms | Chondroitin sulfate proteoglycan core protein, Cytolytic granule proteoglycan core protein, FLJ12930, Hematopoetic proteoglycan core protein, MGC9289, Mastocytoma proteoglycan core protein, OTTHUMP00000019716, P.PG, PG19 core protein, Pgsg, Platelet proteogly, gp600 |
| Swissprot | |
| Cellular Localization | Cytoplasmic granule. Secreted>extracellular space. Golgi apparatus. Found in mast cell granules and in cytoplasmic granules of cytolytic T lymphocytes from where it is secreted upon cell activation. Secreted constitutively by endothelial cells and macrophages. Located to Golgi apparatus during neutrophil differentiation. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:25-1:100 |
Background
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.