SPHK2 Polyclonal Antibody Store at -20°C
SKU: E-AB-10958-200
SPHK2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10958 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SPHK2 |
| Abbre | SPHK2 |
| Synonyms | SK 2, SPHK2, SPK 2, Sphingosine kinase 2, Sphingosine kinase type 2 |
| Swissprot | |
| Calculated MW | 69 kDa |
| Cellular Localization | Cytoplasm. Membrane and Lysosome membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
| IHC | 1:25-1:100 |
Background
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate.Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis.The encoded protein may play a role in breast cancer proliferation and chemoresistance.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.