SHMT2 Polyclonal Antibody
SKU: E-AB-93343-200
SHMT2 Polyclonal Antibody
| SKU # | E-AB-93343 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC, IF, IP |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC, IF, IP |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human SHMT2 |
| Abbre | SHMT2 |
| Synonyms | GLYA, HEL-S-51e, SHMT, serine hydroxymethyltransferase 2, SHMT2 |
| Swissprot | |
| Calculated MW | 53 kDa/54 kDa/55 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Mitochondrion, Mitochondrion inner membrane, Mitochondrion matrix, mitochondrion nucleoid. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:100 |
| IF | 1:50-1:200 |
| IP | 1:50-1:200 |
Background
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.