SETD1A Polyclonal Antibody Reactivity Human
SKU: E-AB-52002-200
SETD1A Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52002 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SETD1A |
| Abbre | SETD1A |
| Synonyms | Histone-lysine N-methyltransferase SETD1A, KMT2F , Lysine N methyltransferase 2F, Lysine N-methyltransferase 2F, SET domain containing 1A, SET domain containing protein 1A, SET domain-containing protein 1A, SET1 , Set1 Ash2 histone methyltransferase comple, hSET1A |
| Swissprot | |
| Cellular Localization | Nucleus speckle. Chromosome. Localizes to a largely non-overlapping set of euchromatic nuclear speckles with SETD1B, suggesting that SETD1A and SETD1B each bind to a unique set of target genes. |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
Background
The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.