SERPINB5 Polyclonal Antibody Store at -20°C
SKU: E-AB-14208-200
SERPINB5 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14208 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SERPINB5 |
| Abbre | SERPINB5 |
| Synonyms | Maspin, Ovalbumin, PI-5, PI5, Peptidase inhibitor 5, Protease inhibitor 5, Serine (or cysteine) peptidase inhibitor, Serpin B5, clade B, clade B (ovalbumin), member 5, protease inhibitor 5 (maspin), serine (or cysteine) proteinase inhibitor, serpin family B m |
| Swissprot | |
| Calculated MW | 42 kDa |
| Cellular Localization | Secreted>extracellular space. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.