RUSC1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52951-200
RUSC1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52951 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human RUSC1 |
| Abbre | RUSC1 |
| Synonyms | DKFZp761A1822, Nesca , New molecule containing SH3 at the carboxy terminus, RUN and SH3 domain containing 1, RUN and SH3 domain containing protein 1, RUSC 1 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Note=Translocated to the nuclear envelope upon stimulation with NGF. |
| Concentration | 1.14 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.