Recombinant Mouse REG2/REG-2 Protein (Fc Tag)
SKU: PKSM040340-100
Recombinant Mouse REG2/REG-2 Protein (Fc Tag)
| SKU # | PKSM040340 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | REG2, RegII |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Met1-Ala173 |
| Accession | NP_033069.1 |
| Calculated Molecular Weight | 43.6 kDa |
| Observed Molecular Weight | 45.4 kDa |
| Tag | C-hFc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
The REG2 Anticoagulation System consists of pegnivacogin, a subcutaneously administered aptamer factor IXa inhibitor, and its intravenous active control agent, anivamersen. The first-in-human study of the effect of the REG2 Anticoagulation System on thrombin generation demonstrates concentration-dependent suppression of thrombin generation that is reversible without rebound effect, as measured by the CAT assay. Full Name.