Recombinant Mouse IL4RA/CD124 Protein (Fc Tag)
SKU: PKSM041368-50
Recombinant Mouse IL4RA/CD124 Protein (Fc Tag)
| SKU # | PKSM041368 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CD124, IL4-BP, IL-4RA, IL-4R-alpha, Interleukin-4 receptor subunit alpha, Soluble IL-4R-alpha, Il4ra, Il4r, IL-4R&, alpha |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Ile26-Arg233 |
| Accession | P16382 |
| Calculated Molecular Weight | 51.5 kDa |
| Observed Molecular Weight | 65-80 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. DLD exists as a homodimer. DLD is involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction. Mutations in its encoding gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.