Recombinant Human SLAMF8 Protein (His Tag)
SKU: PKSH033064-50
Recombinant Human SLAMF8 Protein (His Tag)
| SKU # | PKSH033064 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | B-lymphocyte activator macrophage expressed, BCM-like membrane protein, BLAME, CD353, SLAM family member 8, SLAMF8 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ala23-Asp233 |
| Accession | Q9P0V8 |
| Calculated Molecular Weight | 26.2 kDa |
| Observed Molecular Weight | 34 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
SLAM family member 8 (SLAMF8) is a single-pass type I membrane protein and contains 1 Ig-like C2-type domain. SLAMF8 is a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. SLAMF8 is expressed in lymph node, spleen, thymus and bone marrow. It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.