Recombinant Human/Mouse/Rat BMP-2 Protein
SKU: PKSR030454-100
Recombinant Human/Mouse/Rat BMP-2 Protein
| SKU # | PKSR030454 |
| Expression Host | E.coli |
Description
| Synonyms | BMP-2, BMP-2A, BMP2, BMP2A, Bone Morphogenetic Protein 2, Bone Morphogenetic Protein 2A |
| Species | Human/Mouse/Rat |
| Expression Host | E.coli |
| Sequence | Gln283-Arg396 |
| Accession | P12643 |
| Calculated Molecular Weight | 13.8 kDa |
| Observed Molecular Weight | 14 kDa |
| Tag | C-His |
| Bio-activity | Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is <1.0 μg/mL. |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.