Recombinant Human COL21A1 Protein (His Tag)
SKU: PKSH033712-50
Recombinant Human COL21A1 Protein (His Tag)
| SKU # | PKSH033712 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | COL21A1, COLA1L, DKFZp564B052, FLJ39125, FLJ44623, FP633, MGC26619, alpha 1, alpha 1 type XXI collagen, collagen, collagen alpha-1(XXI) chain, dJ682J15.1, dJ708F5.1, type XXI |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Glu23-Tyr957 |
| Accession | Q96P44 |
| Calculated Molecular Weight | 97.9 kDa |
| Observed Molecular Weight | 115-125&220 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interruptedhelices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, oneTSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in manytissues with the highest expression observed at the fetal stage. COL21A1 is stimulated byPDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type Icollagen; it may serve to maintain the integrity of the extracellular matrix.