Recombinant Human BMP-9 protein(N-His)(active)
SKU: PKSH034136-100
Recombinant Human BMP-9 protein(N-His)(active)
| SKU # | PKSH034136 |
| Expression Host | E.coli |
Description
| Synonyms | NAP-1 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ser 320-Arg 429 |
| Accession | Q9UK05 |
| Calculated Molecular Weight | 12.9 kDa |
| Observed Molecular Weight | 16 kDa |
| Tag | N-His |
| Bio-activity | Measure by its ability to induce alkaline phosphatase production by ATDC5 cells.The ED50 for this effect is <0.4 ng/mL. |
Properties
| Purity | > 98 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 0.01 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.