Recombinant Human BDH2 Protein (His Tag)
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Recombinant Human BDH2 Protein (His Tag)
| SKU # | PKSH032020 |
| Expression Host | E.coli |
Description
| ynonyms | 3-Hydroxybutyrate Dehydrogenase Type 2, BDH2, DHRS6, Dehydrogenase/Reductase SDR Family Member 6, Oxidoreductase UCPA, R-Beta-Hydroxybutyrate Dehydrogenase |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Leu245 |
| Accession | AAH01953.1 |
| Calculated Molecular Weight | 28.9 kDa |
| Observed Molecular Weight | 30 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0. |
| Reconstitution | Not Applicable |
Background
3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of 3-Hydroxybutyrate Dehydrogenase Type 2 make it suitable to conbert high levels of circulating 3-hydroxybutyrate into acetoacetate.